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We more confirmed that CPSI-1306, a small-molecule MIF inhibitor, inhibits the growth of TNBC cells in vitro. Mechanistic scientific tests exposed that CPSI-1306 induces intrinsic apoptosis by alteration in mitochondrial membrane opportunity, cytochrome c (Cyt c) release, and activation of different caspases. In addition, CPSI-1306 inhibits the act